THC-O is a semi-synthetic man-made cannabinoid that has gained popularity for its potency and psychedelic-like properties. Unlike your other legal cannabinoids such as Delta-8, Delta-10, or HHC, THC-O has been reported to provide a much more introspective and spiritual feeling when compared to the other cannabinoids.
Whether you’re looking into THC-O for its medical benefits, recreational use, or are simply interested in what the cannabinoid is, continue reading to find out if THC-O is a fit for you, and what to expect if consumed.
What is THC-O? (Tetrahydrocannabinol-O-acetate)
THC-O, also known as THC-O acetate (or ATHC / THC-Oa), is the acetate ester form of THC. To the average consumer, THC-O is the most common abbreviation, along with THCO or THC O.
One of the biggest differences between THC-O and other THC analogs is the fact that THC-O is a prodrug. This means the compound isn’t activated until it has been metabolized whereas other cannabinoids are pre-activated during heat (decarboxylation). THC-O shares an almost identical chemical structure to Delta-9 THC, which is the compound that causes intoxicating effects in marijuana. Although the effects are similar to D9, THC-O binds tighter to the body’s cannabinoid receptors meaning that it is more intoxicating than the other compounds. Research has been found that THC-O is up to three times stronger than plain ol’ THC.
The extraction is a tedious and dangerous process that involves multiple steps before the final product is created. CBD is first extracted from the raw hemp, and then Delta-8 THC is separated from the CBD and added to acetic anhydride. The final product is THC-O acetate. The production of THC-O is dangerous and should only be performed with the proper experience, safety equipment, and legal authority.
What are the benefits of THC-O?
Most of the information regarding THC-O acetate is based on anecdotal evidence because of the limited research that is available on the compound. Even though most of the evidence is only anecdotal, it is still promising. There have been many reports of euphoric and enjoyable experiences by those who have decided to try THC-O.
Reported benefits of THC-O include:
- Pain Relief
- Increase in Appetite
- Reduced Anxiety
- Euphoria
- Reduced Stress
- Sleep Supportive Qualities
While the evidence out there shows promising opportunities, there is still an abundance of research needed in order to make a reputable and scientific determination regarding the therapeutic and medicinal benefits that THC-O has to offer.
What are the side effects of THC-O?
THC-O acetate has gained popularity among the cannabis community and has been dubbed the “spiritual cannabinoid” for its psychedelic-like experience. There is still a lot unknown about THC-O and its long-term or short-term effects. There are many different factors as well as effects that are unique to each individual depending on how their body reacts to the cannabinoid. Some of the only research on the compound dates back to the 1940s and was found by the US military that THC-O caused dogs’ muscle coordination to deteriorate twice as much as your ordinary Delta-9 THC.
More commonly reported side effects for THC-O include:
- Dizziness & Grogginess
- Nausea & Vomiting
- Seizures
- Sedation & Lethargy
- Increased Sensory Perception
- Hallucinations
- Paranoia
Depending on the dose there can be feelings of both euphoria and sedation. Not only is this compound stronger than other cannabinoids, but as mentioned earlier it needs to be fully processed by the body before anything is felt. It is recommended to proceed with caution due to this reason, because it can be easy for people to consume too much before feeling the full force of the dosage. A general rule of thumb is to wait at least 20-60 minutes for the THC-O to take action before ingesting more. Remember, you can’t take less if you took too much so start small.
Is THC-O Safe?
In the standpoint of production it is a dangerous process that involves acetic anhydride, which is a compound that can create the risk of fire and explosion. It has been recommended by experts to leave the production to those under controlled laboratory conditions with the proper equipment and experience.
For the everyday cannathusiast, there is just not enough research to claim that it is safe. While there have been no reports of a THC-O induced overdose or death, it is easy to over consume which can lead to very undesirable effects.
Another important factor to consider when consuming THC-O is the quality of the product being consumed. There is a lack of regulation in the production of the compound, so it is very important to check third-party lab tests and the certificates of analysis (COAs). It is highly recommended from our team here at Loudest Leaf to ensure valid testing so that the products you consume are safe, and that you’re getting what you expect, not harmful chemicals. We recommend using caution when both buying and consuming THC-O as well as keeping up with the scientific research and regulations involving this cannabinoid.
Is THC-O Legal?
If you haven’t been living under a cannabis rock then you might be familiar with the Farm Bill passed by Congress back in 2018. The bill was signed by former President Donald Trump, and it legalized hemp as well as all of the compounds and derivatives from the plant as long as they contained less than 0.3% Delta-9 THC.
While cannabinoids such as Delta-8 THC are protected under the farm bill, THC-O is in a bit of a gray area because of its synthetic production. The United States Controlled Substances Act (CSA) doesn’t have THC-O specifically listed as a controlled substance, but it could be considered a synthetic analog of THC under the Federal Analog Act , 21 U.S.C. § 813. If this were the case, then the use, production, sale, distribution, and possession would be potentially illegal on a federal level. There are arguments for both sides of THC-O and its legality, but as of now it is still unknown.
You might be wondering if THC-O is legal in your state, so let’s find out. Some states have passed laws that ban psychoactive cannabinoids under the tetrahydrocannabinol (THC) classification in response to the increasing usage of Delta-8 THC as a “legal” alternative to weed. It is safe to assume that states where Delta-8 is banned, THC-O is likely illegal also.
THC-O “might be” illegal in the following states:
- Alaska
- Arizona
- Arkansas
- Colorado
- Delaware
- Idaho
- Iowa
- Mississippi
- Montana
- New York
- Rhode Island
- Utah
- Vermont
It is important to stay up to date with the current rules and regulations surrounding THC-O as information can change at any time. Be sure to check with your state laws before purchasing, consuming, or possessing this cannabinoid.
Will THC-O Cause me to Fail a Drug Test?
While there have been claims that THC-O won’t show up on a drug test due to it being synthetic, drug tests can rarely if at all tell the difference between Delta-9 THC and any of its other analogs. There is a highly probable chance that you’ll test positive if consuming THC-O. While this information isn’t backed by research, it’s not worth losing a job or putting yourself into an unwanted situation. Your best bet is to stay away from THC-O if you’re expecting any sort of drug test.
THC-O Dosage and Consumption Information
Just like when trying anything for the first time, it is always a good idea to start small. With THC-O being even more potent than Delta-9 THC as well as being a prodrug, it is suggested to be on the cautious side when first introducing yourself to the cannabinoid.
THC-O Dosing:
- Beginner Dose: 3 mg oral consumption or 0.5 mg smoked
- Mild Psychoactive Effects
- Standard Dose: 3-10 mg oral consumption or 1-3 mg smoked
- Mild-Moderate Psychoactive Effects
- Heavy “Psychedelic” Dose: 10mg or more oral consumption or 5 mg+ smoked
- Moderate-Very Strong Psychoactive Effects
- Potential Psychedelic Effects
After making a decision on whether or not THC-O is right for you, you might be curious as to what type of products are available for consumption. Currently available products include tinctures, distillates, gummies, dabs, disposable vapes, and vape cartridges. As said previously, always proceed with caution when purchasing and consuming any THC related products.